Otto Heinrich Warburg (Freiburg im Breisgau, 8 October 1883 – Berlin, 1 August 1970) was a German physiologist and physician. He studied the metabolism of tumorsand the dissimilation, particularly in cancer cells. For his discovery and operation of (Warburg's) yellow enzyme, he got in the 1931 Nobel Prize in Physiology or medicine.
Otto Warburg was born in Freiburg, the son of physicist Emil Warburg, president of the Physikalisch Reichsanstalt, and Elizabeth G. He studied chemistry under Emil Fischer at the University of Berlin and received his doctorate there in 1906 with a thesis on polypeptides. He studied medicine under Von Krehl connecting to theUniversity of Heidelberg where he in 1911 with a thesis on oxidation processes earned his second promotion. During the first world war he served in the Prussian horse regiment.
In 1918 Warburg was appointed Professor at the Kaiser Wilhelm Institute (now Max Planck Institute) for natural history near Berlin-Dahlem. Since 1931 he was Director of the Kaiser Wilhelm Institute for cell physiology, which thanks to a donation from the Rockefeller Foundation at the Institute was founded the year before. He retained this position until his death.
Despite his Jewish background (his father Emil was Jewish) ontliep Warburg and his family by persecution during the Second World War his research on cancer and because he enjoyed protection from above. Adolf Hitler had lost his mother to cancer and feared that he got.
In addition, he was editor of and published much in The Metabolism or Tumours (tr. 1931) and wrote New Methods of Cell Physiology (1962). Throughout its 65-year-old career, he wrote 500 scientific articles.
Are many researches and discoveries, often obtained with all-new methods and devices (e.g. the warburg manometer), concerned among other cell respiration,fermentation, photosynthesis and a theory about the development of cancer. Warburg in its Warburg hypothesis assumed that the fundamental difference between normal and cancer cells the ratio of Glycolysis to dissimilation was.
He also wrote The Prime Cause and Prevention of Cancer that he presented at a meeting of Nobel Laureates in Lindauon 30 June 1966. In this lecture presented evidence that anaerobiosis Warburg a first-ever cause of the development of cancer cells. Later research seems to indicate, however, that the findings are a result of the Warburgs mutations of the cancer cell and not the cause of the "uncontrolled growth" in cancer.